1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W026467
    MMV665916
    Inhibitor
    MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 μM and presents the high selectivity index (SI>250).
    MMV665916
  • HY-B0221A
    Amphotericin B trihydrate
    Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures of Streptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity.
    Amphotericin B trihydrate
  • HY-155103
    Antitrypanosomal agent 15
    Inhibitor
    Antitrypanosomal agent 15 (compound 26) is an orally active, brain-penetrant, selective inhibitor against Trypanosoma cruzi proteasome, with an pIC50 of 7.4 and <4 for T. cruzi and human proteasome, respectively. Antitrypanosomal agent 15 has favorable ADME properties and can be used for Chagas disease study.
    Antitrypanosomal agent 15
  • HY-W702966
    Ethopabate-d5
    Ethopabate-d5 (Ethyl pabate-d5) is the deuterium labeled Ethopabate (HY-B2138). Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Ethopabate-d<sub>5</sub>
  • HY-B1370E
    (R)-Hydroxychloroquine phosphate
    Control
    (R)-Hydroxychloroquine ((R)-HCQ) phosphate is a (R)-isomer of Hydroxychloroquine (HY-W031727). (R)-Hydroxychloroquine inhibits the insulin metabolizing enzyme of cytosolic fraction of liver homogenates in healthy and diabetic rats.
    (R)-Hydroxychloroquine phosphate
  • HY-N10769
    Atanine
    Inhibitor
    Atanine is an alkaloid with antiparasitic activity. Atanine can be isolated from medicinal plant, Evodia rutaecarpa.
    Atanine
  • HY-137217
    α-Artemether
    α-Artemether is an antimalarial compound.
    α-Artemether
  • HY-N12636
    Kagimminol A
    Inhibitor
    Kagimminols A is a cembrene-type diterpenoids and can be isolated from an Okeania sp. marine cyanobacterium. Kagimminols A shows selective growth-inhibitory activity against the causative agent of human African trypanosomiasis.
    Kagimminol A
  • HY-B1751D
    Quinidine sulfate dihydrate
    Inhibitor
    Quinidine sulfate dihydrate is an antiarrhythmic agent. Quinidine sulfate dihydrate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine sulfate dihydrate is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinidine sulfate dihydrate can be used for malaria research.
    Quinidine sulfate dihydrate
  • HY-B1071AR
    Lasalocid sodium (Standard)
    Lasalocid (sodium) (Standard) is the analytical standard of Lasalocid (sodium). This product is intended for research and analytical applications. Lasalocid sodium (Lasalocid sodium-A) is an antibacterial and anticoccidial agent that can be used as feed additives. Lasalocid sodium exhibits antitumor activity. Lasalocid sodium is orally active.
    Lasalocid sodium (Standard)
  • HY-147971
    Anticancer agent 75
    Inhibitor
    Anticancer agent 75 is a potent anticancer agent. Anticancer agent 75 shows cytotoxicity and selectivity in cancer cell lines. Anticancer agent 75 shows cytotoxicity to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard. Anticancer agent 75 shows good activity of antiplasmodial.
    Anticancer agent 75
  • HY-B0565S
    Ronidazole-d3
    Inhibitor
    Ronidazole-d3 is the deuterium labeled Ronidazole (HY-B0565). Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus?in cats models. Ronidazole can be used the research of forhistomoniasis?and?swine?dysentery.
    Ronidazole-d<sub>3</sub>
  • HY-145704
    Antimalarial agent 8
    Inhibitor
    Antimalarial agent 8 (Compound 7e) is a novel orally active class of antimalarials. Antimalarial agent 8 is potent in vitro against P. falciparum and is orally efficacious (40 mg/kg) in an in vivo mouse model of malaria.
    Antimalarial agent 8
  • HY-115584S
    Lufenuron-13C6
    Inhibitor
    Lufenuron-13C6 is a 13C-labeled Lufenuron. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods.
    Lufenuron-<sup>13</sup>C<sub>6</sub>
  • HY-B1073R
    Morantel tartrate (Standard)
    Inhibitor
    Morantel (tartrate) (Standard) is the analytical standard of Morantel (tartrate). This product is intended for research and analytical applications.
    Morantel tartrate (Standard)
  • HY-155693
    Topoisomerase II inhibitor 16
    Inhibitor
    Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research.
    Topoisomerase II inhibitor 16
  • HY-176707
    GS​​K2181306A
    Inhibitor
    GSK2181306A is a pan-FIKK inhibitor with an EC50 value of 0.16 μM for parasite growth inhibition. GSK2181306A can be used to study Plasmodium infection.
    GS​​K2181306A
  • HY-Q40175
    Antitrypanosomal agent 9
    Inhibitor
    Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory activity against T. b. brucei, with an IC50 of 1.15 μM. Antitrypanosomal agent 9 can be used for human African trypanosomiasis (HAT) research.
    Antitrypanosomal agent 9
  • HY-125729
    Ivermectin B1b
    Inhibitor 98.66%
    Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture.
    Ivermectin B1b
  • HY-116713
    PfDHODH-IN-3
    PfDHODH-IN-3 (compound 2) is an orally active PfDHODH inhibitor with strong antimalarial activity (IC50=47 nM). PfDHODH-IN-3 can inhibit the growth of Plasmodium in animals.
    PfDHODH-IN-3

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